Azuma N, Tadokoro K, Asaka A, Yamada M, Yamaguchi Y, Handa H, Matsushima S, Watanabe T, Kida Y, Ogura T, Torii M, Shimamura K, Nakafuku M. Transdifferentiation of the retinal pigment epithelia to the neural retina by transfer of the Pax6 transcriptional factor. Hum Mol Genet, 14:1059-1068, 2005. (PubMed)
Azuma N, Tadokoro K, Asaka A, Yamada M, Yamaguchi Y, Handa H, Matsushima S, Watanabe T, Kohsaka S, Kida Y, Shiraishi T, Ogura T, Shimamura K, Nakafuku M. The Pax6 isoform bearing an alternative spliced exon promotes the development of the neural retinal structure. Hum Mol Genet, 14:735-745, 2005. (PubMed) (Self-Archive PDF
including supplemental data)
Nagao K, Togawa N, Fujii K, Uchikawa H, Kohno Y, Yamada M, Miyashita T.
Detecting tissue-specific alternative splicing and disease-associated aberrant
splicing of the PTCH gene with exon junction microarrays. Hum Mol Genet, 14:3379-3388, 2005. (PubMed)
(Self-Archive PDF including supplemental data)
Nagao K, Toyoda M, Takeuchi-Inoue K, Fujii K, Yamada M, Miyashita T. Identification
and characterization of multiple isoforms of a murine and human tumor suppressor,
patched, having distinct first exons. Genomics, 85:462-471, 2005. (PubMed)
Tadokoro K, Yamazaki-Inoue M, Tachibana M, Fujishiro M, Nagao K, Toyoda
M, Ozaki M, Ono M, Miki N, Miyashita T, Yamada M. Frequent occurrence of
protein isoforms with or without a single amino acid residue by subtle
alternative splicing: the case of Gln in DRPLA affects subcellular localization
of the products. J Hum Genet, 50:382-394, 2005. (PubMed)
(Self-Archive PDF) (supplemental data)
Miyashita T. Confocal microscopy for intracellular co-localization of proteins. Methods Mol Biol, 261:399-410, 2004. (PubMed)
Nagao K, Fujii K, Yamada M, Miyashita T. Identification of a novel polymorphism involving a CGG repeat in the PTCH gene and a genome-wide screening of CGG-containing genes. J Hum Genet, 49:97-101, 2004. (PubMed)
(Self-Archive PDF) (supplemental data)
Subramanian RR, Zhang H, Wang H, Ichijo H, Miyashita T, Fu H. Interaction of apoptosis signal-regulating kinase 1 with isoforms of 14-3-3 proteins. Exp Cell Res, 294:581-591, 2004. (PubMed)
U M, Shen L, Oshida T, Miyauchi J, Yamada M, Miyashita T. Identification of novel direct transcriptional targets of glucocorticoid receptor. Leukemia, 18:1850-1856, 2004. (PubMed)
Azuma N, Yamaguchi Y, Handa H, Tadokoro K, Asaka A, Kawase E, Yamada M. Mutations of the PAX6 gene detected in patients with a variety of optic-nerve malformations. Am J Hum Genet, 72:1565-1570, 2003. (PubMed)
Fujii K, Kohno Y, Sugita K, Nakamura M, Moroi Y, Urabe K, Furue M, Yamada M, Miyashita T. Mutations in the human homologue of Drosophila patched in Japanese nevoid basal cell carcinoma syndrome patients. Hum Mutat, 21:451-452, 2003. (PubMed)
Fujii K, Miyashita T, Omata T, Kobayashi K, Takanashi J, Kouchi K, Yamada M, Kohno Y. Gorlin syndrome with ulcerative colitis in a Japanese girl. Am J Med Genet, 121A:65-68, 2003. (PubMed)
Fujino M, Adachi K, Kawasaki M, Kitazawa Y, Funeshima N, Okuyama T, Kimura
H, Li XK. Prolonged survival of rat liver allograft with adenoviral gene
transfection of human immunodeficiency virus type 1 nef. Liver Transpl, 9:805-813, 2003. (PubMed)
Fukuhara Y, Hirasawa A, Li XK, Kawasaki M, Fujino M, Funeshima N, Katsuma
S, Shiojima S, Yamada M, Okuyama T, Suzuki S, Tsujimoto G. Gene expression
profile in the regenerating rat liver after partial hepatectomy. J Hepatol, 38:784-792, 2003. (PubMed)
Kamata Y, Tanabe A, Kanaji A, Kosuga M, Fukuhara Y, Li XK, Suzuki S, Yamada M, Azuma N, Okuyama T. Long-term normalization in the central nervous system, ocular manifestations, and skeletal deformities by a single systemic adenovirus injection into neonatal mice with mucopolysaccharidosis VII. Gene Ther, 10:406-414, 2003. (PubMed)
Kanaji A, Kosuga M, Li XK, Fukuhara Y, Tanabe A, Kamata Y, Azuma N, Yamada M, Sakamaki T, Toyama Y, Okuyama T. Improvement of skeletal lesions in mice with mucopolysaccharidosis type VII by neonatal adenoviral gene transfer. Mol Ther, 8:718-725, 2003. (PubMed)
Miyahara A, Okamura-Oho Y, Miyashita T, Hoshika A, Yamada M. Genomic structure and alternative splicing of the insulin receptor tyrosine kinase substrate of 53-kDa protein. J Hum Genet, 48:410-414, 2003. (PubMed)
(Self-Archive PDF)
Okamura-Oho Y, Miyashita T, Nagao K, Shima S, Ogata Y, Katada T, Nishina H, Yamada M. Dentatorubral-pallidoluysian atrophy protein is phosphorylated by c-Jun NH2-terminal kinase. Hum Mol Genet, 12:1535-1542, 2003. (PubMed)
(Self-Archive PDF)
Shikama Y, Yamada M, Miyashita T. Caspase-8 and caspase-10 activate NF-kappaB through RIP, NIK and IKKalpha kinases. Eur J Immunol, 33:1998-2006, 2003. (PubMed)
Takahashi M, Deb NJ, Kawashita Y, Lee SW, Furgueil J, Okuyama T, Roy-Chowdhury N, Vikram B, Roy-Chowdhury J, Guha C. A novel strategy for in vivo expansion of transplanted hepatocytes using preparative hepatic irradiation and FasL-induced hepatocellular apoptosis. Gene Ther, 10:304-313, 2003. (PubMed)
Takahashi M, Saito H, Atsukawa K, Ebinuma H, Okuyama T, Ishii H. Bcl-2 prevents doxorubicin-induced apoptosis of human liver cancer cells. Hepatol Res, 25:192-201, 2003. (PubMed)
Wu Z, Shen L, Inatomi Y, U M, Miyashita T, Toyama K, Miyauchi J. Effects of TNFalpha on the growth and sensitivity to cytosine arabinoside of blast progenitors in acute myelogenous leukemia with special reference to the role of NF-kappaB. Leuk Res, 27:1009-1018, 2003. (PubMed)
Yanagisawa H, Miyashita T, Nakano Y, Yamamoto D. HSpin1, a transmembrane protein interacting with Bcl-2/Bcl-xL, induces a caspase-independent autophagic cell death. Cell Death Differ, 10:798-807, 2003. (PubMed)
Abe Y, Takamura M, Sawada M, Hisano M, Tsuji Y, Saikawa N, Okuyama T, Odajima Y, Fujita K, Chikaoka H, Iikura Y. Case of insertion, inversion and deletion of chromosome 6. Pediatr Int, 44:530-533, 2002. (PubMed)
Inoue H, Takemura H, Kawai Y, Yoshida A, Ueda T, Miyashita T. Dexamethasone-resistant human Pre-B leukemia 697 cell line evolving elevation of intracellular glutathione level: an additional resistance mechanism. Jpn J Cancer Res, 93:582-590, 2002. (PubMed)
Kurosawa K, Sasaki H, Sato Y, Yamanaka M, Shimizu M, Ito Y, Okuyama T, Matsuo M, Imaizumi K, Kuroki Y, Nishimura G. Paternal UPD14 is responsible for a distinctive malformation complex. Am J Med Genet, 110:268-272, 2002. (PubMed)
Li XK, Kosuga M, Tokieda K, Kanaji A, Fukuhara Y, Hashimoto M, Okabe K, Yaginuma H, Yamada M, Suzuki S, Okuyama T. Prolongation of transgene expression by coexpression of cytokine response modifier a in rodent liver after adenoviral gene transfer. Mol Ther, 5:262-268, 2002. (PubMed)
Sano Y, Yamada J, Ishino Y, Adachi W, Kawasaki S, Suzuki T, Kinoshita S, Okuyama T, Azuma N. Non-cleavable mutant Fas ligand transfection of donor cornea abrogates ocular immune privilege. Exp Eye Res, 75:475-483, 2002. (PubMed)
Shikama Y, Shen L, Yonetani M, Miyauchi J, Miyashita T, Yamada M. Death effector domain-only polypeptides of caspase-8 and -10 specifically inhibit death receptor-induced cell death. Biochem Biophys Res Commun, 291:484-493, 2002. (PubMed)
Yoshida NL, Miyashita T, U M, Yamada M, Reed JC, Sugita Y, Oshida T. Analysis of gene expression patterns during glucocorticoid-induced apoptosis using oligonucleotide arrays. Biochem Biophys Res Commun, 293:1254-1261, 2002. (PubMed)
(Supplemental data)
Cuddeback SM, Yamaguchi H, Komatsu K, Miyashita T, Yamada M, Wu C, Singh S, Wang HG. Molecular cloning and characterization of Bif-1. A novel Src homology 3 domain-containing protein that associates with Bax. J Biol Chem, 276:20559-20565, 2001. (PubMed)
Ebinuma H, Saito H, Kosuga M, Wakabayashi K, Saito Y, Takagi T, Nakamoto N, Okuyama T, Ishii H. Reduction of c-myc expression by an antisense approach under Cre/loxP switching induces apoptosis in human liver cancer cells. J Cell Physiol, 188:56-66, 2001. (PubMed)
Fujino M, Li XK, Guo L, Kitazawa Y, Funeshima N, Fukuda S, Kimura H, Miyashita T, Okuyama T, Amano T, Suzuki S. T-cell apoptosis triggered by FTY720 via mitochondrial pathway. Transplant Proc, 33:3084-3085, 2001. (PubMed)
Fujino M, Li XK, Kitazawa Y, Funeshima N, Guo L, Okuyama T, Amano T, Amemiya H, Suzuki S. Selective repopulation of mice liver after Fas-resistant hepatocyte transplantation. Cell Transplant, 10:353-361, 2001. (PubMed)
Fujino M, Li XK, Suda T, Hashimoto M, Okabe K, Yaginuma H, Mikoshiba K, Guo L, Okuyama T, Enosawa S, Amemiya H, Amano T, Suzuki S. In vitro prevention of cell-mediated xeno-graft rejection via the Fas/FasL-pathway in CrmA-transducted porcine kidney cells. Xenotransplantation, 8:115-124, 2001. (PubMed)
Kamata Y, Okuyama T, Kosuga M, O'hira A, Kanaji A, Sasaki K, Yamada M, Azuma N. Adenovirus-mediated gene therapy for corneal clouding in mice with mucopolysaccharidosis type VII. Mol Ther, 4:307-312, 2001. (PubMed)
Kobayashi S, Uemura H, Kohda T, Nagai T, Chinen Y, Naritomi K, Kinoshita EI, Ohashi H, Imaizumi K, Tsukahara M, Sugio Y, Tonoki H, Kishino T, Tanaka T, Yamada M, Tsutsumi O, Niikawa N, Kaneko-Ishino T, Ishino F. No evidence of PEG1/MEST gene mutations in Silver-Russell syndrome patients. Am J Med Genet, 104:225-231, 2001.(PubMed)
Kosuga M, Sasaki K, Tanabe A, Li XK, Okawa H, Ogino I, Okuda O, Arai H, Sakuragawa N, Kamata Y, Azuma N, Suzuki S, Yamada M, Okuyama T. Engraftment of genetically engineered amniotic epithelial cells corrects lysosomal storage in multiple areas of the brain in mucopolysaccharidosis type VII mice. Mol Ther, 3:139-148, 2001. (PubMed)
Kosuga M, Takahashi S, Tanabe A, Fujino M, Li XK, Suzuki S, Yamada M, Kakishita K, Ono F, Sakuragawa N, Okuyama T. Widespread distribution of adenovirus-transduced monkey amniotic epithelial cells after local intracerebral injection: implication for cell-mediated therapy for lysosome storage disorders. Cell Transplant, 10:435-439, 2001. (PubMed)
Li XK, Fujino M, Sugioka A, Morita M, Okuyama T, Guo L, Funeshima N, Kimura H, Enosawa S, Amemiya H, Suzuki S. Fulminant hepatitis by Fas-ligand expression in MRL-lpr/lpr mice grafted with Fas-positive livers and wild-type mice with Fas-mutant livers. Transplantation, 71:503-508, 2001. (PubMed)
Ohba M, Li XK, Kita Y, Enosawa S, Funeshima N, Nagai H, Zhang H, Okuyama T, Ogoshi S, Sasaguri S, Amemiya H, Suzuki S. Long-term graft acceptance in rat heart transplantation by CTLA4Ig gene transfection combined with FTY720 treatment. World J Surg, 25:391-398, 2001. (PubMed)
Okamura-Oho Y, Miyashita T, Yamada M. Distinctive tissue distribution and phosphorylation of IRSp53 isoforms. Biochem Biophys Res Commun, 289:957-960, 2001. (PubMed)
Shikama Y, U M, Miyashita T, Yamada M. Comprehensive studies on subcellular localizations and cell death-inducing activities of eight GFP-tagged apoptosis-related caspases. Exp Cell Res, 264:315-325, 2001. (PubMed)
U M, Miyashita T, Ohtsuka Y, Okamura-Oho Y, Shikama Y, Yamada M. Extended polyglutamine selectively interacts with caspase-8 and -10 in nuclear aggregates. Cell Death Differ, 8:377-386, 2001. (PubMed)
U M, Miyashita T, Shikama Y, Tadokoro K, Yamada M. Molecular cloning and characterization of six novel isoforms of human Bim, a member of the proapoptotic Bcl-2 family. FEBS Lett, 509:135-141, 2001. (PubMed)
Azuma N, Hirakiyama A, Inoue T, Asaka A, Yamada M. Mutations of a human homologue of the Drosophila eyes absent gene (EYA1) detected in patients with congenital cataracts and ocular anterior segment anomalies. Hum Mol Genet, 9:363-366, 2000. (PubMed)
(Self-Archive PDF)
Komatsu K, Miyashita T, Hang H, Hopkins KM, Zheng W, Cuddeback S, Yamada M, Lieberman HB, Wang HG. Human homologue of S. pombe Rad9 interacts with BCL-2/BCL-xL and promotes apoptosis. Nat Cell Biol, 2:1-6, 2000. (PubMed)
Kosuga M, Enosawa S, Li XK, Suzuki S, Matsuo N, Yamada M, Roy-Chowdhury J, Koiwai O, Okuyama T. Strong, long-term transgene expression in rat liver using chicken beta-actin promoter associated with cytomegalovirus immediate-early enhancer (CAG promoter). Cell Transplant, 9:675-680, 2000. (PubMed)
Kosuga M, Takahashi S, Sasaki K, Enosawa S, Li XK, Okuyama S, Fujino M, Suzuki S, Yamada M, Matsuo N, Sakuragawa N, Okuyama T. Phenotype correction in murine mucopolysaccharidosis type VII by transplantation of human amniotic epithelial cells after adenovirus-mediated gene transfer. Cell Transplant, 9:687-692, 2000. (PubMed)
Kosuga M, Takahashi S, Sasaki K, Li XK, Fujino M, Hamada H, Suzuki S, Yamada M, Matsuo N, Okuyama T. Adenovirus-mediated gene therapy for mucopolysaccharidosis VII: involvement of cross-correction in wide-spread distribution of the gene products and long-term effects of CTLA-4Ig coexpression. Mol Ther, 1:406-413, 2000. (PubMed)
Li XK, Fujino M, Guo L, Okuyama T, Funeshima N, Hashimoto M, Okabe K, Yaginuma H, Mikoshiba K, Enosawa S, Amemiya H, Suzuki S. Inhibition of Fas-mediated fulminant hepatitis in CrmA gene-transfected mice. Biochem Biophys Res Commun, 273:101-109, 2000. (PubMed)
Mitchell KO, Ricci MS, Miyashita T, Dicker DT, Jin Z, Reed JC, El-Deiry WS. Bax is a transcriptional target and mediator of c-myc-induced apoptosis. Cancer Res, 60:6318-6325, 2000. (PubMed)
Muroya K, Okuyama T, Goishi K, Ogiso Y, Fukuda S, Kameyama J, Sato H, Suzuki Y, Terasaki H, Gomyo H, Wakui K, Fukushima Y, Ogata T. Sex-determining gene(s) on distal 9p: clinical and molecular studies in six cases. J Clin Endocrinol Metab, 85:3094-3100, 2000. (PubMed)
Sakuragawa N, Enosawa S, Ishii T, Thangavel R, Tashiro T, Okuyama T, Suzuki S. Human amniotic epithelial cells are promising transgene carriers for allogeneic cell transplantation into liver. J Hum Genet, 45:171-176, 2000. (PubMed)
Yanagisawa H, Bundo M, Miyashita T, Okamura-Oho Y, Tadokoro K, Tokunaga K, Yamada M. Protein binding of a DRPLA family through arginine-glutamic acid dipeptide repeats is enhanced by extended polyglutamine. Hum Mol Genet, 9:1433-1442, 2000. (PubMed)
(Self-Archive PDF)
Azuma N, Yamaguchi Y, Handa H, Hayakawa M, Kanai A, Yamada M. Missense mutation in the alternative splice region of the PAX6 gene in eye anomalies. Am J Hum Genet, 65:656-663, 1999. (PubMed)
Daly TM, Okuyama T, Vogler C, Haskins ME, Muzyczka N, Sands MS. Neonatal intramuscular injection with recombinant adeno-associated virus results in prolonged -glucuronidase expression in situ and correction of liver pathology in mucopolysaccharidosis type VII mice. Hum Gene Ther, 10:85-94, 1999. (PubMed)
Fujii K, Miyashita T, Takanashi J, Sugita K, Kohno Y, Nishie H, Yasumoto S, Furue M, Yamada M. Gamma-irradiation deregulates cell cycle control and apoptosis in nevoid basal cell carcinoma syndrome-derived cells. Jpn J Cancer Res, 90:1351-1357, 1999. (PubMed)
Fujino M, Li XK, Okuyama T, Funeshima N, Tamura A, Enosawa S, Kita Y, Amano T, Yamada M, Amemiya H, Suzuki S. On/off switching Fas-ligand gene expression in liver by Cre/Loxp adenovirus vector system. Transplant Proc, 31:753-754, 1999. (PubMed)
Fujino M, Okuyama T, Li XK, Funeshima N, Tamura A, Enosawa S, Amano T, Amemiya H, Suzuki S. Controlled Fas ligand gene expression by Cre/loxP-mediated switching system: high levels of FasL expression result in lethal hepatitis. Transplant Proc, 31:2695-2696, 1999. (PubMed)
Jin DK, Kang SJ, Kim SJ, Bang EH, Hwang HZ, Tadokoro K, Yamada M, Kohsaka T. Transcriptional regulation of PDGF-A and TGF-beta by +KTS WT1 deletion mutants and a mutant mimicking Denys-Drash syndrome. Ren Fail, 21:685-694, 1999. (PubMed)
Kohsaka T, Tagawa M, Takekoshi Y, Yanagisawa H, Tadokoro K, Yamada M. Exon 9 mutations in the WT1 gene, without influencing KTS splice isoforms, are also responsible for Frasier syndrome. Hum Mutat, 14:466-470, 1999. (PubMed)
Miyashita T, Matsui J, Ohtsuka Y, U M, Fujishima S, Okamura-Oho Y, Inoue T, Yamada M. Expression of extended polyglutamine sequentially activates initiator and effector caspases. Biochem Biophys Res Commun, 257:724-730, 1999. (PubMed)
Negishi K, Azuma N, Yamada M. Various phenotypic expressions of familial aniridia with a PAX6 mutation. Br J Ophthalmol, 83:991-992, 1999. (PubMed)
Okamura-Oho Y, Miyashita T, Ohmi K, Yamada M. Dentatorubral-pallidoluysian atrophy protein interacts through a proline-rich region near polyglutamine with the SH3 domain of an insulin receptor tyrosine kinase substrate. Hum Mol Genet, 8:947-957, 1999. (PubMed)
Takahashi M, Saito H, Okuyama T, Miyashita T, Kosuga M, Sumisa F, Yamada M, Ebinuma H, Ishii H. Overexpression of Bcl-2 protects human hepatoma cells from Fas-antibody-mediated apoptosis. J Hepatol, 31:315-322, 1999. (PubMed)
Azuma N, Hotta Y, Tanaka H, Yamada M. Missense mutations in the PAX6 gene in aniridia. Invest Ophthalmol Vis Sci, 39:2524-2528, 1998. (PubMed)
Azuma N, Yamada M. Missense mutation at the C terminus of the PAX6 gene in ocular anterior segment anomalies. Invest Ophthalmol Vis Sci, 39:828-830, 1998. (PubMed)
Enosawa S, Suzuki S, Li XK, Okuyama T, Fujino M, Amemiya H. Higher efficiency of retrovirus transduction in the late stage of primary culture of hepatocytes from nontreated than from partially hepatectomized rat. Cell Transplant, 7:413-416, 1998. (PubMed)
Li XK, Okuyama T, Tamura A, Enosawa S, Kaneda Y, Takahara S, Funashima N, Yamada M, Amemiya H, Suzuki S. Prolonged survival of rat liver allografts transfected with Fas ligand-expressing plasmid. Transplantation, 66:1416-1423, 1998. (PubMed)
Li XK, Okuyama T, Tamura A, Fujino M, Funeshima N, Kaneda Y, Kita Y, Enosawa S, Amemiya H, Suzuki S. Prolonged survival of recipient rats with Fas-ligand-transfected liver allografts by using HVJ-liposome. Transplant Proc, 30:943, 1998. (PubMed)
Miyashita T, Nagao K, Krajewski S, Salvesen GS, Reed JC, Inoue T, Yamada M. Investigation of glucocorticoid-induced apoptotic pathway: processing of caspase-6 but not caspase-3. Cell Death Differ, 1998;5:1034-1041. (PubMed)
Miyashita T, Nagao K, Ohmi K, Yanagisawa H, Okamura-Oho Y, Yamada M. Intracellular aggregate formation of dentatorubral-pallidoluysian atrophy (DRPLA) protein with the extended polyglutamine. Biochem Biophys Res Commun, 249:96-102, 1998. (PubMed)
Nishita M, Inoue S, Tsuda M, Tateda C, Miyashita T. Nuclear translocation and increased expression of Bax and disturbance in cell cycle progression without prominent apoptosis induced by hyperthermia. Exp Cell Res, 244:357-366, 1998. (PubMed)
Okuyama T, Fujino M, Li XK, Funeshima N, Kosuga M, Saito I, Suzuki S, Yamada M. Efficient Fas-ligand gene expression in rodent liver after intravenous injection of a recombinant adenovirus by the use of a Cre-mediated switching system. Gene Ther, 5:1047-1053, 1998. (PubMed)
Okuyama T, Kosuga M, Takahashi S, Sasaki K, Yamada M. Hepatocyte-specific gene expression by a recombinant adeno-associated virus vector carrying apolipoprotein E enhancer and 1-antitrypsin promoter. Gene Ther Mol Biol,
3:67-74, 1998.
Okuyama T, Li XK, Funeshima N, Fujino M, Sasaki K, Kita Y, Kosuga M, Takahashi M, Saito H, Suzuki S, Yamada M. Fas-mediated apoptosis is involved in the elimination of gene-transduced hepatocytes with E1/E3-deleted adenoviral vectors. J Gastroenterol Hepatol, 13:S113-118, 1998. (PubMed)
Sakai K, Yamada M, Horiba N, Wakui M, Demura H, Suda T. The genomic organization of the human corticotropin-releasing factor type-1 receptor. Gene, 219:125-130, 1998. (PubMed)
Takayama S, Krajewski S, Krajewska M, Kitada S, Zapata JM, Kochel K, Knee D, Scudiero D, Tudor G, Miller GJ, Miyashita T, Yamada M, Reed JC. Expression and location of Hsp70/Hsc-binding anti-apoptotic protein BAG-1 and its variants in normal tissues and tumor cell lines. Cancer Res, 58:3116-3131, 1998. (PubMed)
Yuan ZR, Kohsaka T, Ikegaya T, Suzuki T, Okano S, Abe J, Kobayashi N, Yamada M. Mutational analysis of the Jagged 1 gene in Alagille syndrome families. Hum Mol Genet, 7:1363-1369, 1998. (PubMed)
Harada K, Ishibashi S, Miyashita T, Osuga J, Yagyu H, Ohashi K, Yazaki Y, Yamada N. Bcl-2 protein inhibits oxysterol-induced apoptosis through suppressing CPP32-mediated pathway. FEBS Lett, 411:63-66, 1997. (PubMed)
Miyashita T, Okamura-Oho Y, Mito Y, Nagafuchi S, Yamada M. Dentatorubral pallidoluysian atrophy (DRPLA) protein is cleaved by caspase-3 during apoptosis. J Biol Chem, 272:29238-29242, 1997. (PubMed)
Miyashita T, U M, Inoue T, Reed JC, Yamada M. Bcl-2 relieves the trans-repressive function of the glucocorticoid receptor and inhibits the activation of CPP32-like cysteine proteases. Biochem Biophys Res Commun, 233:781-787, 1997. (PubMed)
Nishiyama K, Nakamura K, Murayama S, Yamada M, Kanazawa I. Regional and cellular expression of the dentatorubral-pallidoluysian atrophy gene in brains of normal and affected individuals. Ann Neurol, 41:599-605, 1997. (PubMed)
Sands MS, Wolfe JH, Birkenmeier EH, Barker JE, Vogler C, Sly WS, Okuyama T, Freeman B, Nicholes A, Muzyczka N, Chang PL, Axelrod HR. Gene therapy for murine mucopolysaccharidosis type VII. Neuromuscul Disord, 7:352-360, 1997. (PubMed)
Yamaguchi Y, Sawada J, Yamada M, Handa H, Azuma N. Autoregulation of Pax6 transcriptional activation by two distinct DNA-binding subdomains of the paired domain. Genes Cells, 2:255-261, 1997. (PubMed)
Azuma N, Nishina S, Yanagisawa H, Okuyama T, Yamada M. PAX6 missense mutation in isolated foveal hypoplasia. Nat Genet, 13:141-142, 1996. (PubMed)
Miki N, Ono M, Murata Y, Ohsaki E, Tamitsu K, Yamada M, Demura H. Regulation of pituitary growth hormone-releasing factor (GRF) receptor gene expression by GRF. Biochem Biophys Res Commun, 224:586-590, 1996. (PubMed)
Potter NT, Yanagisawa H, Yamada M. Different origins of expanded repeats for Haw River syndrome and dentatorubral-pallidoluysian atrophy. Lancet, 347:1271, 1996. (PubMed)
Takano T, Yamanouchi Y, Nagafuchi S, Yamada M. Assignment of the dentatorubral and pallidoluysian atrophy (DRPLA) gene to 12p 13.31 by fluorescence in situ hybridization. Genomics, 32:171-172, 1996. (PubMed)
Yanagisawa H, Fujii K, Nagafuchi S, Nakahori Y, Nakagome Y, Akane A, Nakamura M, Sano A, Komure O, Kondo I, Jin DK, Sorensen SA, Potter NT, Young SR, Nakamura K, Nukina N, Nagao Y, Tadokoro K, Okuyama T, Miyashita T, Inoue T, Kanazawa I, Yamada M. A unique origin and multistep process for the generation of expanded DRPLA triplet repeats. Hum Mol Genet, 5:373-379, 1996. (PubMed)
Komure O, Sano A, Nishino N, Yamauchi N, Ueno S, Kondoh K, Sano N, Takahashi M, Murayama N, Kondo I, Nagafuchi S, Yamada M, Kanazawa I. DNA analysis in hereditary dentatorubral-pallidoluysian atrophy: correlation between CAG repeat length and phenotypic variation and the molecular basis of anticipation. Neurology, 45:143-149, 1995. (PubMed)
Miki N, Ono M, Murata Y, Ohsaki E, Tamitsu K, Ri T, Demura H, Yamada M. Thyroid hormone regulation of gene expression of the pituitary growth hormone-releasing factor receptor. Biochem Biophys Res Commun, 217:1087-1093, 1995. (PubMed)
Nakagawa Y, Yamada M, Ogawa H, Igarashi Y. Missense mutation in CYP11B1 (CGA[Arg-384]→GGA[Gly]) causes steroid 11 beta-hydroxylase deficiency. Eur J Endocrinol, 132:286-289, 1995. (PubMed)
Ono M, Miki N, Murata Y, Osaki E, Tamitsu K, Ri T, Yamada M, Demura H. Sexually dimorphic expression of pituitary growth hormone-releasing factor receptor in the rat. Biochem Biophys Res Commun, 216:1060-1066, 1995. (PubMed)
Tanaka M, Hirai H, LoVerde PT, Nagafuchi S, Franco GR, Simpson AJ, Pena SD. Yeast artificial chromosome (YAC)-based genome mapping of Schistosoma mansoni. Mol Biochem Parasitol, 69:41-51, 1995. (PubMed)
Yazawa I, Nukina N, Hashida H, Goto J, Yamada M, Kanazawa I. Abnormal gene product identified in hereditary dentatorubral-pallidoluysian atrophy (DRPLA) brain. Nat Genet, 10:99-103, 1995. (PubMed)
Akiyama K, Kanda N, Yamada M, Tadokoro K, Matsunaga T, Nishi Y. Megabase-scale analysis of the origin of N-myc amplicons in human neuroblastomas. Nucleic Acids Res, 22:187-193, 1994. (PubMed)
Burke JR, Ikeuchi T, Koide R, Tsuji S, Yamada M, Pericak-Vance MA, Vance JM. Dentatorubral-pallidoluysian atrophy and Haw River syndrome. Lancet, 344:1711-1712, 1994. (PubMed)
Imamura A, Ito R, Tanaka S, Fukutomi O, Shimozawa N, Nishimura M, Suzuki Y, Kondo N, Yamada M, Orii T. High-intensity proton and T2-weighted MRI signals in the globus pallidus in juvenile-type of dentatorubral and pallidoluysian atrophy. Neuropediatrics, 25:234-237, 1994. (PubMed)
Nagafuchi S, Yanagisawa H, Ohsaki E, Shirayama T, Tadokoro K, Inoue T, Yamada M. Structure and expression of the gene responsible for the triplet repeat disorder, dentatorubral and pallidoluysian atrophy (DRPLA). Nat Genet, 8:177-182, 1994. (PubMed)
Nagafuchi S, Yanagisawa H, Sato K, Shirayama T, Ohsaki E, Bundo M, Takeda T, Tadokoro K, Kondo I, Murayama N, Tanaka Y, Kikushima H, Umino K, Kurosawa H, Furukawa T, Nihei K, Inoue T, Sano A, Komure O, Takahashi M, Yoshizawa T, Kanazawa I, Yamada M. Dentatorubral and pallidoluysian atrophy expansion of an unstable CAG trinucleotide on chromosome 12p. Nat Genet, 6:14-18, 1994. (PubMed)
Odawara M, Sasaki K, Nagafuchi S, Tanae A, Yamashita K. Lack of association between mitochondrial gene mutation np 3243 and type 1 diabetes mellitus and autoimmune thyroid diseases. Lancet, 344:1086, 1994. (PubMed)
Ono M, Miki N, Demura H, Tadokoro K, Nagafuchi S, Yamada M. Molecular cloning of cDNA encoding the precursor for hamster hypothalamic growth hormone-releasing factor. DNA Seq, 5:93-102, 1994. (PubMed)
Akiyama K, Kanda N, Yamada M, Kato M, Tadokoro K, Matsunaga T, Nishi Y. Structural organization of MYCN amplicons of neuroblastoma tumors, xenografts, and cell lines characterized by the sequences encompassing the MYCN amplicons in a human neuroblastoma cell line. Genes Chromosomes Cancer, 8:15-21, 1993. (PubMed)
Fukutani K, Kajiwara T, Nagafuchi S, Nakahori Y, Nakagome Y. Detection of the testis determining factor in an XX man. J Urol, 149:126-128, 1993. (PubMed)
Iwai I, Suda T, Tozawa F, Nakano Y, Sato Y, Ohmori N, Sumitomo T, Yamada M, Demura H. Stimulatory effect of Saireito on proopiomelanocortin gene expression in the rat anterior pituitary gland. Neurosci Lett, 157:37-40, 1993. (PubMed)
Komuro H, Hayashi Y, Kawamura M, Hayashi K, Kaneko Y, Kamoshita S, Hanada R, Yamamoto K, Hongo T, Yamada M, Tsuchida Y. Mutations of the p53 gene are involved in Ewing's sarcomas but not in neuroblastomas. Cancer Res, 53:5284-5288, 1993. (PubMed)
Nagafuchi S, Namiki M, Nakahori Y, Kondoh N, Okuyama A, Nakagome Y. A minute deletion of the Y chromosome in men with azoospermia. J Urol, 150:1155-1157, 1993. (PubMed)
Nakagawa Y, Takeuchi H, Kubota A, Nakahori Y, Nakagome Y, Igarashi Y, Yamada M. Restriction fragment length polymorphisms of the CYP11B1 gene in the Japanese population. Jpn J Hum Genet, 38:203-207, 1993. (PubMed)
Sakai A, Tadokoro K, Yanagisawa H, Nagafuchi S, Hoshikawa N, Suzuki T, Kohsaka T, Hasegawa T, Nakahori Y, Yamada M. A novel mutation of the WT1 gene (a tumor suppressor gene for Wilms' tumor) in a patient with Denys-Drash syndrome. Hum Mol Genet, 2:1969-1970, 1993. (PubMed)
Suda T, Tozawa F, Dobashi I, Horiba N, Ohmori N, Yamakado M, Yamada M, Demura H. Corticotropin-releasing hormone, proopiomelanocortin, and glucocorticoid receptor gene expression in adrenocorticotropin-producing tumors in vitro. J Clin Invest, 92:2790-2795, 1993. (PubMed)
Suda T, Tozawa F, Iwai I, Sato Y, Sumitomo T, Nakano Y, Yamada M, Demura H. Neuropeptide Y increases the corticotropin-releasing factor messenger ribonucleic acid level in the rat hypothalamus. Brain Res Mol Brain Res, 18:311-315, 1993. (PubMed)
Tadokoro K, Oki N, Sakai A, Fujii H, Ohshima A, Nagafuchi S, Inoue T, Yamada M. PCR detection of 9 polymorphisms in the WT1 gene. Hum Mol Genet, 2:2205-2206, 1993. (PubMed)
Akane A, Seki S, Shiono H, Nakamura H, Hasegawa M, Kagawa M, Matsubara K, Nakahori Y, Nagafuchi S, Nakagome Y. Sex determination of forensic samples by dual PCR amplification of an X-Y homologous gene. Forensic Sci Int, 52:143-148, 1992. (PubMed)
Fukazawa R, Nakahori Y, Kogo T, Kawakami T, Akamatsu H, Tanae A, Hibi I, Nagafuchi S, Nakagome Y, Hirayama T. Normal Y sequences in Smith-Lemli-Opitz syndrome with total failure of masculinization. Acta Paediatr, 81:570-572, 1992. (PubMed)
Kondoh S, Miyake Y, Nakahori Y, Nakagome Y, Kaneda Y. Cytogenetical and molecularbiological studies on a bovine XY female.
J Vet Med Sci, 54:1077-1080, 1992. (PubMed)
Ishijima SA, Okuno M, Nakahori Y, Seki S, Nagafuchi S, Kaneko S, Mohri H. Identification of X- and Y-chromosome-bearing human sperm separated by free-flow electrophoresis using Y-chromosome-specific polymerase chain reaction. Biomed. Res, 13:221-224, 1992.
Nagafuchi S, Tamura T, Nakahori Y, Takano K, Nishi Y, Iwatani N, Kitao M, Hori Y, Konda S, Hasegawa T, Numabe H, Fujieda K, Tanaka T, Hibi I, Nakagome Y. The majority of the marker chromosomes in Japanese patients with stigmata of Turner syndrome are derived from Y chromosomes. Hum Genet, 89:590-592, 1992. (PubMed)
Nagafuchi S, Nakahori Y, Nakamura Y, England SB, Tamura T, Numabe H, Nakagome Y. Localization of 24 cosmid clones on the human Y chromosome. Jpn J Hum Genet, 37:307-310, 1992. (PubMed)
Nagafuchi S, Seki S, Nakahori Y, Tamura T, Numabe H, Nakagome Y. PCR detection of structurally abnormal Y chromosomes. Jpn J Hum Genet, 37:187-193, 1992. (PubMed)
Nakagome Y, Young SR, Akane A, Numabe H, Jin DK, Yamori Y, Seki S, Tamura T, Nagafuchi S, Shiono H, et al. A Y-associated allele may be characteristic of certain ethnic groups in Asia. Ann Hum Genet, 56:311-314, 1992. (PubMed)
Namiki M, Uchida K, Okuyama A, Nagafuchi S, Tamura T, Nakagome Y. Deoxyribonucleic acid study on 2 XX male patients. J Urol, 147:633-635, 1992. (PubMed)
Numabe H, Nagafuchi S, Nakahori Y, Tamura T, Kiuchi H, Namiki M, Kohda
N, Fukushima Y, Fuse H, Kusano M, Arai T, Matsuzaki Y, Fukutani K, Isurugi
K, Kuroki Y, Ikeuchi T, Yoshida M, Minowada S, Nakagome Y. DNA analyses
of XX and XX-hypospadiac males. Hum Genet, 90:211-124, 1992. (PubMed)
Sekine T, Fukutani K, Motegi T, Hayakawa H, Tamura T, Nagafuchi S, Nakahori Y, Nakagome Y. DNA analysis of two patients with a non-fluorescent Y chromosome.
Jpn J Hum Genet, 37:157-162, 1992. (PubMed)
Suda T, Sato Y, Sumitomo T, Nakano Y, Tozawa F, Iwai I, Yamada M, Demura H. Beta-endorphin inhibits hypoglycemia-induced gene expression of corticotropin-releasing factor in the rat hypothalamus. Endocrinology, 130:1325-1330, 1992. (PubMed)
Suda T, Nakano Y, Tozawa F, Sumitomo T, Sato Y, Yamada M, Demura H. The role of corticotropin-releasing factor and vasopressin in hypoglycemia-induced proopiomelanocortin gene expression in the rat anterior pituitary gland. Brain Res, 579:303-309, 1992. (PubMed)
Tadokoro K, Fujii H, Ohshima A, Kakizawa Y, Shimizu K, Sakai A, Sumiyoshi K, Inoue T, Hayashi Y, Yamada M. Intragenic homozygous deletion of the WT1 gene in Wilms' tumor. Oncogene, 7:1215-1221, 1992. (PubMed)
Tadokoro K, Oki N, Fujii H, Ohshima A, Inoue T, Yamada M. Genomic organization of the human WT1 gene. Jpn J Cancer Res, 83:1198-1203, 1992. (PubMed)
Agematsu K, Nakahori Y. Recipient origin of bone marrow-derived fibroblastic stromal cells during all periods following bone marrow transplantation in humans. Brit J Haematol, 79:359-365, 1991. (PubMed)
Akane A, Shiono H, Matsubara K, Nakahori Y, Seki S, Nagafuchi S, Yamada M, Nakagome Y. Sex identification of forensic specimens by polymerase chain reaction (PCR): two alternative methods. Forensic Sci Int, 49:81-88, 1991. (PubMed)
Akane A, Matsubara K, Shiono H, Yamada M, Nakagome Y. Diagnosis of twin zygosity by hypervariable RFLP markers. Am J Med Genet, 41:96-98, 1991. (PubMed)
Fuse H, Satomi S, Kazama T, Katayama T, Nagabuchi S, Tamura T, Nakahori Y, Nakagome Y. DNA hybridization study using Y-specific probes in an XX-male. Andrologia, 23:237-239, 1991. (PubMed)
Lagerstrom M, Dahl N, Nakahori Y, Nakagome Y, Backman B, Landegren U, Pettersson U. A deletion in the amelogenin gene (AMG) causes X-linked amelogenesis imperfecta (AIH1). Genomics, 10:971-975, 1991. (PubMed)
Nakagome Y, Seki S, Nagafuchi S, Nakahori Y, Sato K. Absence of fetal cells in maternal circulation at a level of 1 in 25,000. Am J Med Genet, 40:506-508, 1991. (PubMed)
Nakagome Y, Seki S, Fukutani K, Nagafuchi S, Nakahori Y, Tamura T. PCR detection of distal Yp sequences in an XX true hermaphrodite. Am J Med Genet, 41:112-114, 1991. (PubMed)
Nakagome Y, Nagafuchi S, Seki S, Nakahori Y, Tamura T, Yamada M, Iwaya M. A repeating unit of the DYZ1 family on the human Y chromosome consists of segments with partial male-specificity. Cytogenet Cell Genet, 56:74-77, 1991. (PubMed)
Nakahori Y, Takenaka O, Nakagome Y. A human X-Y homologous region encodes "amelogenin". Genomics, 9:264-269, 1991. (PubMed)
Nakahori Y, Tamura T, Nagafuchi S, Fujieda K, Minowada S, Fukutani K, Fuse H, Hayashi K, Kuroki Y, Fukushima Y, Agematsu K, Kuno T, Kaneko S, Yamada K, Kitagawa T, Nonomura M, Fukuda S, Kusano M, Onigata S, Hibi I, Nakagome Y. Molecular cloning and mapping of 10 new probes on the human Y chromosome. Genomics, 9:765-769, 1991. (PubMed)
Nakahori Y, Hamano K, Iwaya M, Nakagome Y. Sex identification by polymerase chain reaction using X-Y homologous primer. Am J Med Genet, 39:472-473, 1991. (PubMed)
Osada H, Kawata M, Yamada M, Okumura K, Takamizawa H. Genetic identification of pregnancies responsible for choriocarcinomas after multiple pregnancies by restriction fragment length polymorphism analysis. Am J Obstet Gynecol, 165:682-688, 1991. (PubMed)
Shinohara M, Minowada S, Aso Y, Yamada K, Nakahori Y, Tamura T, Nakagome Y. A t(Y;15) translocation with a deletion of the proximal Yq in a boy with mixed gonadal dysgenesis. Hum Genet, 86:442-444, 1991. (PubMed)
Sumitomo T, Suda T, Nakano Y, Tozawa F, Yamada M, Demura H. Angiotensin II increases the corticotropin-releasing factor messenger ribonucleic acid level in the rat hypothalamus. Endocrinology, 128:2248-2252, 1991. (PubMed)
Tadokoro K, Kato M, Yokota S, Yamada M. TaqI RFLPs at the Wilms' tumor gene (WT1). Nucleic Acids Res, 19:2514, 1991. (PubMed)
Tadokoro K, Fujii H, Inoue T, Yamada M. Polymerase chain reaction (PCR) for detection of ApaI polymorphism at the insulin like growth factor II gene (IGF2). Nucleic Acids Res, 19:6967, 1991. (PubMed)
Tamura T, Kuroki Y, Nagafuchi S, Suwa S, Nakahori Y, Terashima K, Furusho T, Nakagome Y. DNA analysis of a patient with two different marker chromosomes using Y-specific DNA probes. Jinrui Idengaku Zasshi (Jpn J Hum Genet), 36:195-199, 1991. (PubMed)
Yoshida M, Kakizawa Y, Moriyama N, Minowada S, Higashihara E, Aso Y, Nakagome Y, Nakahori Y, Nagafuchi S, Tanae A. Deoxyribonucleic acid and cytological detection of Y-containing cells in an XX hypospadiac boy with polyorchidism. J Urol, 146:1356-1358, 1991. (PubMed)
Agematsu K, Kitahara F, Uehara Y, Kawai H, Miyagawa Y, Komiyama A, Nakahori Y, Nakagome Y, Akabane T. Detection of engraftment and chimerism after bone marrow transplantation by in situ hybridization using a Y-chromosome specific probe. Am J Hematol, 33:255-260, 1990. (PubMed)
Akane A, Matsubara K, Shiono H, Yuasa I, Yokota S, Yamada M, Nakagome Y. Paternity testing: blood group systems and DNA analysis by variable number of tandem repeat markers. J Forensic Sci, 35:1217-1225, 1990. (PubMed)
Akane A, Nakajima H, Shiono H, Matsubara K, Yamada M, Nakagome Y. A case of maternity testing: exclusion by polymorphic VNTR markers of DNA. Jinrui Idengaku Zasshi (Jpn J Hum Genet), 35:319-323, 1990. (PubMed)
Nakagome Y, Nagafuchi S, Nakahori Y. Prenatal sex determination. Lancet, 335:291, 1990. (Pub Med)
Nakamura Y, Sakai K, Sakuma S, Sato E, Maruyama M, Hashimoto T, Fukuda S, Nishimi Y, Nakagome Y, Nakahori Y, Yamada M. Partial trisomy of the distal segment 14q. Hum Genet, 84:574-576, 1990. (PubMed)
Suda T, Tozawa F, Ushiyama T, Sumitomo T, Yamada M, Demura H. Interleukin-1 stimulates corticotropin-releasing factor gene expression in rat hypothalamus. Endocrinology, 126:1223-1228, 1990. (PubMed)
Young SR, Nakahori Y, Tamura T, Nakagome Y. Probe 87-10a identifies a codominantly inherited X chromosome allele polymorphic in three racial populations. Nucleic Acids Res, 18:3113, 1990. (PubMed)
Fujii Y, Matui Y, Nakagawa Y, Hongo T, Igarashi Y, Yamada M, Nakagome Y, Tobayama S. Translocation t(12;16)(q13;p11) in myxoid liposarcoma of a child and implication of the human int-1 gene in tumorigenesis. Jpn J Cancer Res, 80:958-962, 1989. (PubMed)
Hayashi Y, Inaba T, Hanada R, Yamada M, Nakagome Y, Yamamoto K. Similar chromosomal patterns and lack of N-myc gene amplification in localized and IV-S stage neuroblastomas in infants. Med Pediatr Oncol, 17:111-115, 1989. (PubMed)
Nagai K, Koike S, Kominami R, Muramatsu M, Nakahori Y, Nakagome Y, Soma H, Yanagisawa I. The characterization of human male-specific 5.7 kb DNA(pKY-1) and its application to fetal sex-determination probe. Jinrui Idengaku Zasshi (Jpn J Hum Genet), 34:261-267, 1989. (PubMed)
Nakagome Y, Nakahori Y, Tamura T, Yamada M. DNA diagnosis in medicine. Asian Med J,
32:490-496, 1989.
Nakahori Y, Tamura T, Yamada M, Nakagome Y. Two 47z [DXYS5] RFLPs on the X and the Y chromosome. Nucleic Acids Res, 17:2152, 1989. (PubMed)
Nakahori Y, Yamada M, Nakagome Y. Very low rate Y-chromosome mosaicism (1:5,400) detectable by a novel probe enzyme combination. Jinrui Idengaku Zasshi (Jpn J Hum Genet), 34:203-208, 1989. (PubMed)
Suda T, Tozawa F, Ushiyama T, Tomori N, Sumitomo T, Nakagami Y, Yamada M, Demura H, Shizume K. Effects of protein kinase-C-related adrenocorticotropin secretagogues and interleukin-1 on proopiomelanocortin gene expression in rat anterior pituitary cells. Endocrinology, 124:1444-1449, 1989. (PubMed)
Yokoi T, Sagisaka K, Nakahori Y, Nakagome Y. Hypervariable polymorphism of autosomal origin detected by the Y-chromosome derived probe, pHY10. Jinrui Idengaku Zasshi (Jpn J Hum Genet), 34:209-215, 1989. (PubMed)
Agematsu K, Koike K, Morosawa H, Nakahori Y, Nakagome Y, Akabane T. Chondrodysplasia punctata with X;Y translocation. Hum Genet, 80:105-107, 1988. (PubMed)
Kobayashi R, Nakauchi H, Nakahori Y, Nakagome Y, Matsuzawa S. Sex identification in fresh blood and dried bloodstains by a nonisotopic deoxyribonucleic acid (DNA) analyzing technique. J Forensic Sci, 33:613-620, 1988. (PubMed)
Morisaki H, Morisaki T, Nakahori Y, Ogura H, Kanno H, Tani K, Kodo H, Fujii H, Asano S, Miwa S. Genotypic analysis using a Y-chromosome-specific probe following bone marrow transplantation. Am J Hematol, 27:30-33, 1988. (PubMed)
Suda T, Tozawa F, Yamada M, Ushiyama T, Tomori N, Sumitomo T, Nakagami Y, Demura H, Shizume K. Insulin-induced hypoglycemia increases corticotropin-releasing factor messenger ribonucleic acid levels in rat hypothalamus. Endocrinology, 123:1371-1375, 1988. (PubMed)
Suda T, Tozawa F, Yamada M, Ushiyama T, Tomori N, Sumitomo T, Nakagami Y, Demura H, Shizume K. Effects of corticotropin-releasing hormone and dexamethasone on proopiomelanocortin messenger RNA level in human corticotroph adenoma cells in vitro. J Clin Invest, 82:110-114, 1988. (PubMed)
Suda T, Tozawa F, Yamada M, Ushiyama T, Tomori N, Sumitomo T, Nakagami Y, Shizume K. In vitro study on proopiomelanocortin messenger RNA levels in cultured rat anterior pituitary cells. Life Sci, 42:1147-1152, 1988. (PubMed)
Tozawa F, Suda T, Yamada M, Ushiyama T, Tomori N, Sumitomo T, Nakagami Y, Demura H, Shizume K. Insulin-induced hypoglycemia increases proopiomelanocortin messenger ribonucleic acid levels in rat anterior pituitary gland. Endocrinology, 122:1231-1235, 1988. (PubMed)
Yamada M, Kurosawa H, Nakagawa Y, Nakagome Y, Tsuda T, Higashi K. Amplified allele of the human N-myc oncogene in neuroblastomas. Jpn J Cancer Res, 79:670-673, 1988. (PubMed)
*Kato J, Nishimura Y, Yamada M, Suzuki H, Hirota Y. Gene organization in
the region containing a new gene involved in chromosome partition in Escherichia
coli. J Bacteriol, 170:3967-3977, 1988. (PubMed)
Kurosawa H, Yamada M, Nakagome Y. Restriction fragment length polymorphisms of the human N-myc gene: relationship to gene amplification. Oncogene, 2:85-90, 1987. (PubMed)
Morisaki H, Morisaki T, Nakahori Y, Ogura H, Kanno H, Tani K, Fujii H, Asano S, Miwa S. Use of Y-chromosome specific probe for detection of engraftment of bone marrow transplantation. Nippon Ketsueki Gakkai Zasshi (Acta Haematol Jpn), 50:1254-1257, 1987. (PubMed)
Nakagome Y, Yamada M, Kurosawa H, Jinno N, Hayashi Y, Suzuki A, Nakahori Y, Nakajo T, Morikawa Y, Nagahara N. DNA studies in 109 malignant tumors in children. Acta Paediatr Jpn, 29:542-545, 1987. (PubMed)
Yamada M. Maximal expression of cloned human genes in cultured mammalian cells. In "New Approach to Genetic Diseases" (Sasazuki
T. ed.). pp. 151-159, Academic Press, Tokyo, 1987.
Mitani K, Kurosawa H, Suzuki A, Hayashi Y, Hanada R, Yamamoto K, Komatsu A, Kobayashi N, Nakagome Y, Yamada M. Amplification of N-myc in a rhabdomyosarcoma. Jpn J Cancer Res, 77:1062-1065, 1986. (PubMed)
Nakagome Y, Nakahori Y, Mitani K, Matsumoto M. The loss of centromeric heterochromatin from an inactivated centromere of a dicentric chromosome. Jinrui Idengaku Zasshi (Jpn J Hum Genet), 31:21-26, 1986. (PubMed)
Nakahori Y, Mitani K, Yamada M, Nakagome Y. A human Y-chromosome specific repeated DNA family (DYZ1) consists of a tandem array of pentanucleotides. Nucleic Acids Res, 14:7569-7580, 1986. (PubMed)
Takano T, Nakagome Y, Nagafuchi S, Tanaka F, Nakamura Y, Nagano T, Tanae A, Hibi I. High-resolution cytogenetic studies in patients with Prader-Willi syndrome. Clin Genet, 30:241-248, 1986. (PubMed)
Nakagome Y, Nagahara N. High-resolution studies in patients with aniridia-Wilms tumor association. Hum Genet, 70:289, 1985. (PubMed)
*Yamada M, Lewis JA, Grodzicker T. Overproduction of the protein product of a nonselected foreign gene carried by an adenovirus vector. Proc Natl Acad Sci U S A, 82:3567-3571, 1985. (PubMed)
*Nakagome Y, Ise T, Sakurai M, Nakajo T, Okamoto E, Takano T, Nakahori Y, Tsuchida Y, Nagahara N, Takada Y, Ohsawa Y, Sawaguchi S, Toyosaka A, Kobayashi N, Matsunaga E, Saito S. High-resolution studies in patients with aniridia-Wilms tumor association, Wilms tumor or related congenital abnormalities. Hum Genet, 67:245-248, 1984. (PubMed)
*Nakahori Y, Nakagome Y. A malformed girl with duplication of chromosome
9q. J Med Genet, 21:387-388, 1984. (PubMed)
* indicates that the report was published by a staff member at his/her previous organization.
Department of Genetics, National Research Institute for Child Health and Development
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